HUANG Zhong-Xian

    Male, born on March 7, 1940. In 1962 he graduated from Department of Chemistry of Fudan University and completed his postgraduate study in Inorganic Chemistry in Fudan University. He took teaching duty in the Department of Chemistry. In 1980-1981 he was academic visitor in Department of Chemistry of University of Wales, U.K. and the following year (1981-1982) in Department of Inorganic Chemistry of University of Oxford, U.K. He was promoted to be the Associate Professor position in the Chemistry Department of Fudan University in 1985. In 1991-1992 he worked in Beckman Institute of California Institute of Technology, U.S.A.. Since 1993 he is a full Professor and Ph.D. program supervisor of Chemistry Department of Fudan University. In 1999, he was invited to be a Visiting Professor of Institute of Material Science of Nagoya University, Japan.

He was the Director of Inorganic Chemistry Division and Deputy Dean of Graduate School of Fudan University. Now he is the Vice-Chief-Editor of 'Chinese Journal of Chemistry' (English Edition), and is also the member of Editor Board of Chinese Journal of Inorganic Chemistry. He is a member of evaluation experts committee of Molecular Biology and Biochemistry and Inorganic Chemistry of NSF of China, member of academic board of the State Key Laboratory on Coordination Chemistry at Nanjing University and the State Key Laboratory on Bio-organic Chemistry at Shanghai Institute of Organic Chemistry of Science Academy of China. 

Tel: (021) 65643973      Fax: (021) 65641740     E-mail: zxhuang@fudan.edu.cn

Research Field:

Metal ions in biological systems including metal complexes with biological significance (structure and stability of biological metal compounds, antitumor metal complexes and amino acids and peptide metal complexes); the structure, function and mechanism of metalloproteins especially on the metallothioneins, electron transfer proteins and DNA regulation proteins.

The number of papers published in journals home and abroad: 100 Selected publications: (in the recent 5 years)

1.  The Influence of Mutation at Glu44 and 56 of Cytochrome b₅ on the Protein's Stabilization and Interaction between Cytochrome c and Cytochrome b₅.

     Biochemistry, 37 (1998), 14137-14150.  

2.  Structure, Interaction and Electron Transfer between Cytochrome b₅, Its E44A and/or E56A Mutants and Cytochrome c.

     J. Mol. Biol., 285 (1999), 347-359. 

3.  Effect of Mutation at Valine 61 on the Three-Dimensional Structure, Stability, and Redox Potential of Cytochrome b₅.

     Biochemistry, 38 (1999), 11961-11972.  

4.  The effect of mutation at valine-45 on the stability and redox potentials of trypsin-cleaved cytochrome b₅. Biophysical Chemistry, 83(1) (2000), 3-17.  

5.  Effects of Some Charged Amino Acid Mutations on the Electron Self-Exchange Kinetics of Cytochrome b₅.

    Inorg. Chem., 38 (1999), 5749-5754.